Summary of results
- Lactiplantibacillus plantarum DR7 significantly reduces the number, duration and severity ENT infections.
- She increases salivary IgA levels, strengthening local mucosal immunity.
- She is well tolerated and remains effective in stressful situations.
- THE magnesium And Fibersol complement the immune effect by supporting the nervous system and intestinal balance.
- The whole formula acts in synergy to strengthen natural defenses.
Synergistic benefits and documented mechanisms
The formula composed of Lactiplantibacillus plantarum DR7, magnesium bisglycinate, Fibersol And HPMC vegetable capsules shows real potential to support immunity and prevention of ENT (otolaryngeal) infections, although not all components act directly at this level.
Here are the clinical evidence available, especially for the DR7 strain.
1. Lactiplantibacillus plantarum DR7
It is the only ingredient in the formula to have been specifically studied for its immune and preventive effect on upper respiratory tract infections (ENT).
Major clinical study:
Lee et al. (2021) – “Lactobacillus plantarum DR7 reduces incidence and duration of upper respiratory tract infections in stressed adults.”
Design : Randomized, double-blind, placebo-controlled study on 111 healthy adults subjected to psychological stress (factor promoting ENT infections).
Results :
. Significant decrease in the number of ENT infectious episodes
. Reduction in the duration of symptoms (cold, sore throat)
. Decreased severity of symptoms
. Improvement of immune markers (increase in salivary IgA)
- Publication : Beneficial Microbes, 12(1), 81–8
2. Magnesium Bisglycinate
Although not specific to ENT infections, magnesium is essential for the proper functioning of the immune system. He supports:
- T cell and macrophage activity
- Regulation of the inflammatory response
- Reduction of oxidative stress (aggravating factor in ENT infections)
Immunomodulatory effects are documented in:
- Tam et al. (2003) – “Magnesium and the immune system”, Magnesium Research, 16(1), 43–50
- Nielsen (2010) – “Magnesium, inflammation, and immunity”, Magnesium Research, 23(1), 1–8
Fibersol (resistant corn dextrin)
Fibersol does not act directly on ENT infections, but it acts as prebiotic support :
- Promotes the growth of good bacteria (including L.plantarum)
- Participate in the regulation of the local immune response
- Reduction of intestinal inflammation (indirect effect on the intestine-immunity-ENT axis)
Conclusion
There strain L. plantarum DR7 is supported by a robust clinical study demonstrating a reduction in ENT infections. The other components (magnesium bisglycinate, Fibersol) indirectly reinforce the formula by supporting overall immunity and gut health.